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apalutamide will reduce the extent or impact of ethinylestradiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay clear of or Use Alternate Drug. Coadministration of apalutamide, a solid CYP3A4 inducer, with medicines that happen to be CYP3A4 substrates may lead to decrease publicity to these medications.It’s not legitimate that W